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Merck
CN

SML4221

Ofloxacin hydrochloride

≥98% (HPLC), powder, fluoroquinolone antibiotic

别名:

9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hydrochloride, (±)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hydrochloride, Ofloxacin HCl

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关于此项目

经验公式(希尔记法):
C18H20FN3O4 · xHCl
化学文摘社编号:
分子量:
361.37 (free base basis)
MDL number:
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

O=C(O)C1=CN2C3=C(OCC2C)C(N4CCN(C)CC4)=C(F)C=C3C1=O.[xHCl]

General description

Ofloxacinhydrochloride is a broad-spectrum fluoroquinolone antibiotic that exhibitswater solubility, whereas ofloxacin itself is only sparingly soluble in aqueoussolutions.

Application

Ofloxacin hydrochloride may be used as a standard to study theadsorption behaviour of antibiotics.

Biochem/physiol Actions

Ofloxacin kills bacteria by blocking DNA gyrase and type IV topoisomerase—critical enzymes for DNA replication and transcription—leading to cell death. Ofloxacin has 100 times higher affinity for bacterial DNA gyrase than for mammalian. It is effective against a broad array of both Gram-positive and Gram-negative bacteria, in addition to Mycoplasmas.

Disclaimer

Hygroscopic Store with desiccant


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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