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关于此项目
经验公式（希尔记法）:
C18H20FN3O4 · xHCl
化学文摘社编号:
分子量:
361.37 (free base basis)
MDL number:
NACRES:
NA.21
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear
storage temp.
-10 to -25°C
SMILES string
O=C(O)C1=CN2C3=C(OCC2C)C(N4CCN(C)CC4)=C(F)C=C3C1=O.[xHCl]
General description
Ofloxacinhydrochloride is a broad-spectrum fluoroquinolone antibiotic that exhibitswater solubility, whereas ofloxacin itself is only sparingly soluble in aqueoussolutions.
Application
Ofloxacin hydrochloride may be used as a standard to study theadsorption behaviour of antibiotics.
Biochem/physiol Actions
Ofloxacin kills bacteria by blocking DNA gyrase and type IV topoisomerase—critical enzymes for DNA replication and transcription—leading to cell death. Ofloxacin has 100 times higher affinity for bacterial DNA gyrase than for mammalian. It is effective against a broad array of both Gram-positive and Gram-negative bacteria, in addition to Mycoplasmas.
Disclaimer
Hygroscopic Store with desiccant
警示词
Warning
危险代码
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
闪点 (F)
Not applicable
闪点 (°C)
Not applicable