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关于此项目
经验公式（希尔记法）:
C19H24O3
化学文摘社编号:
分子量:
300.39
MDL number:
NACRES:
NA.21
UNSPSC Code:
12352200
eCl@ss:
32160703
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
General description
Artepillin C (ARC) is a prenylated derivative of p-coumaric acid. It is one of the primary phenolic compounds present in Brazilian green propolis (BGP) and Baccharis dracunculifolia. It is a p-CA derivative, featuring two prenyl groups linked to the meta-positions (C3 and C5) of the phenyl ring.
Application
Artepillin C may be used to investigate its interaction with human serum albumin (HSA) and to understand its physicochemical transport mechanism in vitro.
Biochem/physiol Actions
Phenolic component of propolis that exhibits multiple activities including anti-inflammatory, anti-tumor, antimicrobial and antioxidant activities; inhibitor of CREB-CRTC2 interaction. The anti-cancer properties of ARC are due to several mechanisms, including the induction of apoptosis, cell cycle arrest, and the inhibition of p21-activated kinase 1 (PAK1).
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存储类别
11 - Combustible Solids
WGK
WGK 3