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SML4235

MTSEA-Biotin-XX

Name: MTSEA-Biotin-XX
Brand: SIGMA

≥98% (HPLC), powder, Thiol-reactive probe

别名:

MTSEA-xx-Biotin, Biotin-XX-MTSEA, S-(2-(6-(6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)hexanamido)ethyl) methanesulfonothioate

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关于此项目

经验公式（希尔记法）:

C₂₅H₄₅N₅O₆S₃

化学文摘社编号:

1217447-71-6

分子量:

607.85

UNSPSC Code:

12352200

Assay:

≥98% (HPLC)

Form:

powder

Storage condition:

desiccated

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属性

Quality Segment

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

shipped in

wet ice

storage temp.

-10 to -25°C

说明

General description

MTSEA biotin-XX is a membrane-impermeant crosslinker consisting of biotin-coupled 2-aminoethyl-methanethiosulfonate (MTSEA).

Application

MTSEA-Biotin-XX may be used to covalently label cysteine residues in proteins or thiol-containing molecules with a biotin tag for streptavidin-based detection, purification, or accessibility studies and, for biotinylation of 4TU‐labeled RNAs in direct RNA sequencing.

Biochem/physiol Actions

MTSEA-Biotin-XX selectively and efficiently labels cell surface thiols, including cysteine residues and specific RNA modifications (s4U and dm6A), forming disulfide bonds with enhanced reactivity. The extended -XX- linker facilitates optimal biotin-streptavidin interaction, while the overall structure allows for high-yield, rapid reactions. Biotin-XX-MTSEA enables imaging, purification, and sequencing applications through its ability to tag target molecules via methanethiosulfonate (MTS) reactions.

Disclaimer

Hygroscopic, Store with desiccant

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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