Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
General description
Potent and selective high-affinity allosteric inhibitor of amino acid transporter B0AT1 (SLC6A19) (IC50 = 31nM).
JX225 is a potent and selective high-affinity allosteric inhibitor of amino acid transporter B0AT1 (SLC6A19) (IC50 = 31nM). JX225 binds to an allosteric binding site in the vestibule of the transporter, which prevents conformational change necessary for channel opening.
JX225 is a potent and selective high-affinity allosteric inhibitor of amino acid transporter B0AT1 (SLC6A19) (IC50 = 31nM). JX225 binds to an allosteric binding site in the vestibule of the transporter, which prevents conformational change necessary for channel opening.
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable