跳转至内容

主要文件

查看所有文档

SML4273

Nimustine hydrochloride

≥95% (HPLC)

别名:

N′-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(2-chloroethyl)-N-nitroso-urea, 1-(4-Amino-2-methylpyrimidin-5-yl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride, Nimustine hydrochloride, ACNU hydrochloride, Nidran hydrochloride

登录并加购，请在购物车里查看协议价、货期和发货地。

选择规格

变更视图

关于此项目

经验公式（希尔记法）:
C9H13ClN6O2 · xHCl
分子量:
272.69 (free base basis)
Assay:
≥95% (HPLC)
Form:
powder
Storage condition:
desiccated
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

Quality Segment

100

assay

≥95% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

Nimustine HCl (ACNU) is a brain-penetrating nitrosourea that kills cancer cells by damaging their DNA. Nimustine HCl forms O6-chloroethylguanine adducts, which cross-link with other DNA strands, blocking replication and leading to cell death. Nimustine also suppresses blood cell production and is often used in combination with other chemotherapy drugs. Nimustine undergoes conversion into several active metabolites, including denitrosated ACNU, 3-((4-amino-2-methylpyrimidin-5-yl)methyl)-4-hydroxy-1-nitrosoimidazolidin-2-one, 1-(2-chloroethyl)-1-nitrosourea and 1-((4-amino-2-methylpyrimidin-5-yl)methyl)-5-hydroxyimidazolidin-2-one.

Disclaimer

Hygroscopic Store with desiccant

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Muta. 2 - Skin Sens. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库