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Merck
CN

SML4311

Biotin Alkyne

new

≥95% (HPLC)

别名:

(3aS,4S,6aR)-Hexahydro-2-oxo-N-2-propyn-1-yl-1H-thieno[3,4-d]imidazole-4-pentanamide, Biotin propargylamide, N-Propargylbiotinamide

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关于此项目

经验公式(希尔记法):
C13H19N3O2S
化学文摘社编号:
分子量:
281.37
UNSPSC代码:
12352200
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质量水平

方案

≥95% (HPLC)

表单

powder

储存条件

desiccated

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear (warmed)

储存温度

-10 to -25°C

一般描述

Enables selective biotinylation of azide-containing biomolecules via CuAAC for robust detection, purification, and immobilization.
Biotin Alkyne (N-Propargylbiotinamide) is a non-cleavable, alkyne-activated biotinylation reagent that enables selective labeling of azide-containing biomolecules via copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC). The terminal alkyne reacts with azides to form a stable triazole linkage, facilitating permanent biotin conjugation to proteins, nucleic acids, or other targets. Biotin provides high-affinity interactions with streptavidin or avidin for detection, purification, or immobilization and, being preferentially taken up by cancer cells, serves as an excellent guiding molecule to tumor cells, enabling targeted detection and delivery. This reagent enables site-specific bioconjugation on cell surfaces, in lysates, or in vitro, excelling in bio- and chemical sensing to deliver reliable results in proteomics and molecular biology workflows.

免责声明

Hygroscopic Store with dessicant

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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