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SML4369

DSSO-Carbamate

≥95% (NMR)

别名:

DSSO-carbamate Crosslinker, bis-(2,5-Dioxopyrrolidin-1-yl) (sulfinylbis(ethane-2,1-diyl))dicarbamate

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关于此项目

经验公式(希尔记法):
C14H18N4O9S
分子量:
418.38
UNSPSC Code:
12352200
Assay:
≥95% (NMR)
Form:
powder
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Quality Segment

assay

≥95% (NMR)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

shipped in

wet ice

storage temp.

-10 to -25°C

Biochem/physiol Actions

DSSO-carbamate is an advanced crosslinker optimized for cross-linking mass spectrometry (XL-MS) applications, offering superior chemical stability and reactivity compared to DSSO. By replacing ester groups with carbamates, it resists retro-Michael degradation, ensuring higher recovery rates for crosslinks and monolinks under physiological conditions. This enhanced performance facilitates precise structural mapping of flexible and multiconformational proteins, significantly improving integration with computational tools like AlphaFold2. DSSO-carbamate’s improved sensitivity, stability, and structural accuracy make it a valuable addition for proteomics, particularly in resolving dynamic protein conformations and interactions.


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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