SRP0313
FBXL10 human
recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE)
别名:
CXXC2, FBXL10, JHDM1B, KDM2B, lysine (K)-specific demethylase 2B
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关于此项目
NACRES:
NA.32
UNSPSC Code:
12352202
Biological source:
human
Recombinant:
expressed in baculovirus infected Sf9 cells
Assay:
≥80% (SDS-PAGE)
Form:
aqueous solution
Mol wt:
75 kDa
产品名称
FBXL10 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE)
biological source
human
recombinant
expressed in baculovirus infected Sf9 cells
assay
≥80% (SDS-PAGE)
form
aqueous solution
mol wt
75 kDa
packaging
pkg of 20 μg
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... KDM2B(84678)
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
General description
Human F-Box Protein 10 (FBXL10, also known as KDM2B, JHDM1B, CXXC2, and Histone-H3 K36 demethylase 1B), (GenBank Accession No. NM_032590), amino acids 1-650 with C-terminal FLAG-tag, MW= 75 kDa, expressed in Sf9 cells via a Baculovirus expression system.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Neil P Blackledge et al.
Molecular cell, 38(2), 179-190 (2010-04-27)
In higher eukaryotes, up to 70% of genes have high levels of nonmethylated cytosine/guanine base pairs (CpGs) surrounding promoters and gene regulatory units. These features, called CpG islands, were identified over 20 years ago, but there remains little mechanistic evidence
Yuji Tanaka et al.
The EMBO journal, 29(9), 1510-1522 (2010-04-10)
The rate-limiting step in ribosome biogenesis is the transcription of ribosomal RNA, which is controlled by environmental conditions. The JmjC enzyme KDM2A/JHDM1A/FbxL11 demethylates mono- and dimethylated Lys 36 of histone H3, but its function is unclear. Here, we show that
David Frescas et al.
Cell cycle (Georgetown, Tex.), 7(22), 3539-3547 (2008-11-13)
Heterochromatin plays an essential role in the preservation of epigenetic information, the transcriptional repression of repetitive DNA elements and inactive genes, and the proper segregation of chromosomes during mitosis. Here we identify KDM2A, a JmjC-domain containing histone demethylase, as a
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