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Merck
CN

SRP0321

JMJD2D active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE)

别名:

KDM4D, lysine (K)-specific demethylase 4D

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关于此项目

NACRES:
NA.32
UNSPSC Code:
12352202
Form:
aqueous solution
Assay:
≥90% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in baculovirus infected Sf9 cells
Mol wt:
67 kDa
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biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

assay

≥90% (SDS-PAGE)

form

aqueous solution

mol wt

67 kDa

packaging

pkg of 100 μg

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... KDM4D(55693)

General description

Human JMJD2D, also known as KDM4D (GenBank Accession No. NM_018039), amino-acids 2-354 with N-terminal GST tag, MW=67 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Masuko Katoh et al.
International journal of oncology, 24(6), 1623-1628 (2004-05-13)
JMJD1 family genes, including JMJD1 (TSGA), TRIP8, and C5orf7 (5qNCA), encode nuclear proteins with Jumonji C (JmjC), TRI8H1 and TRI8H2 domains. Here, we identified JMJD2 family genes. Human genes corresponding to KIAA0677, KIAA0876, KIAA0780 and FLJ10251 cDNAs were designated JMJD2A
Sook Shin et al.
Biochemical and biophysical research communications, 353(4), 973-977 (2007-01-09)
JMJD2A-D belong to the JmjC domain-containing family of histone demethylases. JMJD2D is the most structurally divergent JMJD2 protein as it lacks the PHD and Tudor domains present in JMJD2A-C. Here, we systematically analyzed the histone demethylase specificity of JMJD2 proteins

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