SRP0334
ITK active rat
recombinant, expressed in baculovirus infected Sf9 cells, ≥58% (SDS-PAGE)
别名:
IL2-inducible T-cell kinase
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关于此项目
Assay:
≥58% (SDS-PAGE)
Biological source:
rat
Recombinant:
expressed in baculovirus infected Sf9 cells
产品名称
ITK active rat, recombinant, expressed in baculovirus infected Sf9 cells, ≥58% (SDS-PAGE)
biological source
rat
recombinant
expressed in baculovirus infected Sf9 cells
assay
≥58% (SDS-PAGE)
form
aqueous solution
mol wt
57 kDa
packaging
pkg of 10 μg
technique(s)
activity assay: suitable
inhibition assay: suitable
NCBI accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
rat ... Itk(363577)
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
General description
Rat recombinant IL2-inducible T-cell kinase (ITK), also known as Lyk and TSK (GenBank AccessionNo. NM_001108825), amino acids 352-620 (end) with N-terminal GST-tag, MW= 57 kDa, expressed in Sf9 cells via a Baculovirus expression system.
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Characterization of Itk tyrosine kinase: contribution of noncatalytic domains to enzymatic activity.
J Hawkins et al.
Protein expression and purification, 22(2), 211-219 (2001-07-05)
Itk is a Tec family tyrosine kinase found in T cells that is activated upon ligation of the T cell receptor (TCR/CD3), CD2, or CD28. Itk contains five domains in addition to the catalytic domain: pleckstrin homology, Tec homology which
N Tanaka et al.
FEBS letters, 324(1), 1-5 (1993-06-07)
We have cloned a novel human protein tyrosine kinase gene specific to T cells by the polymerase chain reaction method. This gene encodes a 620 amino-acid polypeptide including a catalytic domain for tyrosine kinase, an SH2 domain and an SH3
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