SRP0336
SYK Catalytic Subunit active human
recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE)
别名:
p72-Syk, spleen tyrosine kinase
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关于此项目
Specific activity:
≥139 pmol/min-μg
Assay:
≥60% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in baculovirus infected Sf9 cells
产品名称
SYK Catalytic Subunit active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE)
biological source
human
recombinant
expressed in baculovirus infected Sf9 cells
assay
≥60% (SDS-PAGE)
form
aqueous solution
specific activity
≥139 pmol/min-μg
mol wt
58 kDa
packaging
pkg of 10 μg
technique(s)
activity assay: suitable
inhibition assay: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... SYK(6850)
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
General description
Recombinant human SYK, (Genbank Accession No. NM_003177), amino acids 359-635 (end) with an N-terminal GST-tag, MW = 58 kDa, expressed in Sf9 insect cells.
Physical form
Fomulated in 40 mM Tris-HCl, pH 8, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 4 mM glutathione, and 20% glycerol.
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Tomoko Takano et al.
Antioxidants & redox signaling, 4(3), 533-541 (2002-09-07)
Oxidative stress induces the activation of multiple signaling pathways related to various cellular responses. In B cells, Syk has a crucial role in intracellular signal transduction induced by oxidative stress as well as antigen receptor engagement. Treatment of B cells
Christopher S Navara
Current pharmaceutical design, 10(15), 1739-1744 (2004-06-08)
The spleen tyrosine kinase Syk is an enigmatic protein tyrosine kinase functional in a number of diverse cellular processes. It is best known as a non receptor protein tyrosine kinase involved in signal transduction in cells of hematopoietic origin and
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