产品名称
EZH2 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥49% (SDS-PAGE)
biological source
human
recombinant
expressed in baculovirus infected Sf9 cells
assay
≥49% (SDS-PAGE)
form
aqueous solution
mol wt
114 kDa
packaging
pkg of 20 μg
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... EZH2(2146)
General description
Human EZH2 (GenBank Accession No. NM_004456), amino acids 2-end with N-terminal His-GST-tag, MW= 114 kDa, expressed in a Sf9 Baculovirus expression system.
Physical form
Formulated in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 16 mM glutathione, 20% glycerol and 3 mM DTT.
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Zheng Zhang et al.
Nucleic acids research, 45(16), 9348-9360 (2017-06-24)
In eukaryotic cells, the gene expression status is strictly controlled by epigenetic modifications on chromatin. The repressive status of chromatin largely contributes to HIV latency. Studies have shown that modification of histone H3K27 acts as a key molecular switch for
Rakotobe, D. et al.
Journal of Virology, 5, 32-32 (2008)
Sooryanarayana Varambally et al.
Science (New York, N.Y.), 322(5908), 1695-1699 (2008-11-15)
Enhancer of zeste homolog 2 (EZH2) is a mammalian histone methyltransferase that contributes to the epigenetic silencing of target genes and regulates the survival and metastasis of cancer cells. EZH2 is overexpressed in aggressive solid tumors by mechanisms that remain
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