产品名称
MLL1/WDR5/Ash2L/RbBP5/DPY30 human, recombinant, expressed in E. coli, ≥83% (SDS-PAGE)
biological source
human
recombinant
expressed in E. coli
assay
≥83% (SDS-PAGE)
form
aqueous solution
mol wt
12 kDa (DPY30)
27 kDa (MLL1)
35 kDa (WDR5)
60 kDa (RbBP5)
61 kDa (Ash2L)
packaging
pkg of 50 μg
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... ASH2L(9070), DPY30(84661), MLL(4297), RBBP5(5929), WDR5(11091)
General description
MLL1/WARD complex of human MLL1 (GenBank Accession No. NM_005933) amino acids 3745-end with N-terminal His-tag, MW= 27 kDa, human WDR5 (GenBank Accession No. NM_017588), amino acids 22-end with N-terminal Flagtag, MW= 35 kDa, human Ash2L (GenBank Accession No. NM_001105214), amino acids 2-end with N-terminal His-tag, MW= 61 kDa, human RbBP5 (GenBank Accession No. NM_005057), amino acids 2-end with N-terminal His-tag, MW= 60 kDa, and human DPY30 (GenBank Accession No. NM_032574), amino acids 2-end with N-terminal His-tag, MW=12 kDa, individually expressed in an E. coli expression system.
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Anamika Patel et al.
The Journal of biological chemistry, 284(36), 24242-24256 (2009-06-27)
Transcription in eukaryotic genomes depends on enzymes that regulate the degree of histone H3 lysine 4 (H3K4) methylation. The mixed lineage leukemia protein-1 (MLL1) is a member of the SET1 family of H3K4 methyltransferases and is frequently rearranged in acute
Man Mohan et al.
Nature reviews. Cancer, 10(10), 721-728 (2010-09-17)
The RNA polymerase II (Pol II) elongation factor (ELL) was the first translocation partner of mixed lineage leukaemia (MLL) for which a biochemical function was determined. It was therefore proposed that the regulation of the elongation stage of transcription could
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持