方案
≥90% (HPLC)
表单
aqueous solution
包装
pkg of 500 μL
浓度
200 μM
运输
dry ice
储存温度
−70°C
一般描述
Histones have an important role in the organization and modification of chromatin. The nucleosome is the basic unit of the chromatin. It is made up of two molecules each of histones H2A, H2B, H3 and H4 wrapped with approximately 146bp of DNA. Histone H1 binds to the nucleosomes at the DNA entry and exit points and stabilizes them. The gene encoding this protein is localized on human chromosome 6p22.2.
应用
Study enzyme kinetics, and screen small molecular inhibitors of PRMT for drug discovery and HTS applications.
其他说明
500 μL at 200 μM, or 100 nmol Sold as 500 μL
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
A Comprehensive View of the Epigenetic Landscape Part I: DNA Methylation, Passive and Active DNA Demethylation Pathways and Histone Variants
Anna Sadakierska-Chudy
Neurotoxicity Research, 27, 84-97 (2015)
The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly.
Ahmad K and Henikoff S
Molecular Cell, 9(6), 1191-1200 (2002)
Core histones H2B and H4 are mobilized during infection with herpes simplex virus 1.
Conn KL, et al.
Journal of Virology, 85(24), 13234-13252 (2011)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持