SRP0429
PDE4A10 active human
recombinant, expressed in baculovirus infected Sf9 cells, ≥75% (SDS-PAGE)
别名:
DPDE2, PDE46, phosphodiesterase 4A, cAMP-specific
生物来源
human
重组
expressed in baculovirus infected Sf9 cells
方案
≥75% (SDS-PAGE)
表单
aqueous solution
比活
≥75% (compared to standard)
分子量
117 kDa
包装
pkg of 10 μg
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... PDE4A(5141)
一般描述
Human PDE4A10, also known as PDE4A protein isoform 6, transcript variant 3 (GenBank Accession No. NM_001111309) amino acids 2-825 (end) with N-terminal GST-tag, MW= 117 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
应用
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
其他说明
One unit is defined as the amount of enzyme that will convert 1 pmole of 3?, 5?-cAMP to 5?-AMP per min at 37°C.
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
I McPhee et al.
Cellular signalling, 13(12), 911-918 (2001-12-01)
In situ hybridisation methods were used to map the distribution of the novel long PDE4A10 isoform in the brain. PDE4A10 distribution was compared to that of the long PDE4A5 isoform and the short PDE4A1 isoform using probes specific for unique
Angela McCahill et al.
Cellular signalling, 20(11), 2071-2083 (2008-08-30)
Transcripts for the PDE4A10 cyclic AMP phosphodiesterase isoform are present in a wide variety of rat tissues including the heart. Sequence comparisons between the putative human and mouse promoters revealed a number of conserved regions including both an Sp1 and
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