SRP0437
PDE7B active rat
recombinant, expressed in baculovirus infected Sf9 cells, ≥30% (SDS-PAGE)
别名:
phosphodiesterase 7B
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关于此项目
NACRES:
NA.32
UNSPSC Code:
12352200
Assay:
≥30% (SDS-PAGE)
Biological source:
rat
Recombinant:
expressed in baculovirus infected Sf9 cells
产品名称
PDE7B active rat, recombinant, expressed in baculovirus infected Sf9 cells, ≥30% (SDS-PAGE)
biological source
rat
recombinant
expressed in baculovirus infected Sf9 cells
assay
≥30% (SDS-PAGE)
form
aqueous solution
mol wt
65 kDa
packaging
pkg of 10 μg
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
rat ... PDE7B(140929)
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
General description
Rat PDE7B (GenBank Accession No. NM_080894) amino acids 108-446 (end) with N-terminal GST-tag, MW=65 kDa, expressed in a Baculovirus-infected Sf9 cell expression system.
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
E Reyes-Irisarri et al.
Neuroscience, 132(4), 1173-1185 (2005-04-29)
cAMP plays an important role as second messenger molecule controlling multiple cellular processes in the brain. cAMP levels depend critically on the phosphodiesterases (PDE) activity, enzymes responsible for the clearance of intracellular cAMP. We have examined the regional distribution and
Lingzhi Zhang et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(49), 19532-19537 (2008-11-27)
Cyclic nucleotide phosphodiesterase (PDE) isoforms can influence disease pathogenesis and be novel therapeutic targets. Because lower cAMP levels may contribute to the decreased apoptosis that occurs in chronic lymphocytic leukemia (CLL), we assessed the expression levels of PDE isoforms in
C Gardner et al.
Biochemical and biophysical research communications, 272(1), 186-192 (2000-06-29)
We have identified and characterised a novel member of the PDE7 family of cyclic nucleotide phosphodiesterases (PDE), which we have designated PDE7B. Mouse and human full-length cDNAs were isolated encoding a protein of 446 and 450 amino acids, respectively. The
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