SRP0456
BRD3 (306-417) His tag human
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
别名:
ORFX, RING3L, bromodomain containing 3
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关于此项目
NACRES:
NA.32
UNSPSC Code:
12352200
Form:
aqueous solution
Assay:
≥90% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in E. coli
Mol wt:
14.1 kDa
产品名称
BRD3 (306-417) His tag human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
biological source
human
recombinant
expressed in E. coli
assay
≥90% (SDS-PAGE)
form
aqueous solution
mol wt
14.1 kDa
packaging
pkg of 100 μg
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... BRD3(8019)
General description
Human Bromodomain containing 3, also known as BRD3 or RING3L (GenBank Accession No. NM_007371) amino-acids 306 – 417 with N-terminal HIS-tag, MW = 14.1 kDa, expressed in an E. coli expression system.
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Janine M Lamonica et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(22), E159-E168 (2011-05-04)
Acetylation of histones triggers association with bromodomain-containing proteins that regulate diverse chromatin-related processes. Although acetylation of transcription factors has been appreciated for some time, the mechanistic consequences are less well understood. The hematopoietic transcription factor GATA1 is acetylated at conserved
Roland Gamsjaeger et al.
Molecular and cellular biology, 31(13), 2632-2640 (2011-05-11)
Recent data demonstrate that small synthetic compounds specifically targeting bromodomain proteins can modulate the expression of cancer-related or inflammatory genes. Although these studies have focused on the ability of bromodomains to recognize acetylated histones, it is increasingly becoming clear that
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