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Merck
CN

SRP0462

BRD4 (342-460) His tag human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

别名:

CAP, HUNK1, HUNKI, MCAP, bromodomain containing 4

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关于此项目

NACRES:
NA.32
UNSPSC Code:
12352200
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产品名称

BRD4 (342-460) His tag human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

biological source

human

recombinant

expressed in E. coli

assay

≥90% (SDS-PAGE)

form

aqueous solution

mol wt

14.7 kDa

packaging

pkg of 100 μg

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... BRD4(23476)

General description

Human Bromodomain containing 4, also known as BRD4, HUNK1, or MCAP (GenBank Accession No. NM_058243) amino-acids 342-460 with N-terminal His-tag, MW = 14.7 kDa, expressed in an E. coli expression system.

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Philipp Voigt et al.
Genome biology, 12(11), 133-133 (2011-12-01)
The chromatin adapter BRD4 may be crucial for transmitting epigenetic information by acting as a histone acetylation-dependent gene bookmark and accelerating post-mitotic transcriptional reactivation.
R M Rodriguez et al.
Journal of molecular medicine (Berlin, Germany), 90(5), 587-595 (2011-11-29)
The bromodomain protein BRD4 is involved in cell proliferation and cell cycle progression, primarily through its role in acetylated chromatin-dependent regulation of transcription at targeted loci. Here, we show that BRD4 is frequently downregulated by aberrant promoter hypermethylation in human

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