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Merck
CN

SRP0711

ROR1, Active

PRECISIO® Kinase, recombinant

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关于此项目

NACRES:
NA.77
UNSPSC Code:
12352202
Form:
frozen liquid
Assay:
70-95% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells
Mol wt:
~82 kDa
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产品名称

ROR1, Active, PRECISIO® Kinase, recombinant

recombinant

expressed in baculovirus infected Sf9 cells

assay

70-95% (SDS-PAGE)

form

frozen liquid

specific activity

0.2-1.0 nmol/min·mg (radiometric)

mol wt

~82 kDa

concentration

0.1 μg/μL

accession no.

NM_005012

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... ROR1(4919)

Biochem/physiol Actions

Recombinant human ROR1(429-end) was expressed by Baculovirus in Sf9 insect cells using an N-terminal GST tag. ROR1 is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors that play a role in the control of most basic cellular processes including cell proliferation, differentiation, migration and metabolism (1). Many human breast cancers express the ROR1 protein and high-level expression of ROR1 in breast adenocarcinoma is associated with aggressive disease. Silencing expression of ROR1 in human breast cancer cell lines found to express this protein impaired their growth in vitro and also in immune-deficient mice (2).

Preparation Note

Store in aliquots at -70°C. Avoid freeze/thaw cycles.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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