重组
expressed in baculovirus infected Sf9 cells
方案
70-95% (SDS-PAGE)
表单
frozen liquid
比活
15-25 nmol/min·mg (radiometric)
分子量
~69 kDa
浓度
0.05-0.1 μg/μL
登记号
NM_001024401
运输
dry ice
储存温度
−70°C
基因信息
human ... SBK1(388228)
应用
Useful for kinase assay.
生化/生理作用
Full-length recombinant human SBK1 was expressed by Baculovirus in Sf9 insect cells using an N-terminal GST tag. SBKI or SH3 domain binding kinase 1 is a novel serine/threonine protein kinase structurally related to a Xenopus gastrula-specific protein kinase, Pk9.7 which possessing a consensus sequence for an SH3-binding domain from developing rat brain and it play an important role in signal-transduction pathways related to the control of brain development (1). SBK1 may predict a broad cellular function, and its dysregulated in certain cancers suggests an involvement of the protein in the pathogenesis of human cancers (2).
制备说明
Formulated in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.
Store in aliquots at -70°C. Avoid freeze/thaw cycles.
法律信息
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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