SRP2036
BRG1, wild type human
recombinant, expressed in insect cells, ≥80% (SDS-PAGE)
别名:
BAF190, BRG1, FLJ39786, RTPS2, SNF2, SNF2-beta, SNF2L4, SNF2LB, SWI2, hSNF2b
生物来源
human
重组
expressed in insect cells
方案
≥80% (SDS-PAGE)
表单
frozen liquid
分子量
~185 kDa
包装
pkg of 5 μg
储存条件
avoid repeated freeze/thaw cycles
浓度
300 μg/mL
颜色
clear
colorless
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... SMARCA4(6597)
生化/生理作用
The wild type human brahma-related gene 1 (Brg1) encodes a protein of 1,647 amino acids that contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription regulation. BRG1 is an essential component of the SWI/SNF chromatin remodeling complexes and implicated in multiple functions through its interaction with different proteins, including the tumor suppressor protein pRb, serine-threonine kinase LKB1, and other transcription factors. Although Brg1 is involved in chromatin remodeling as a complex with other SWI/SNF proteins, purified BRG1 itself is capable of remodeling mono-nucleosomes and nucleosomal arrays in vitro. Mutations of Brg1 have been found in multiple tumor cell lines.
外形
Clear and colorless frozen liquid solution
制备说明
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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