SRP2075
SRC1, FLAG tagged, TEV site human
recombinant, expressed in E. coli, ≥80% (SDS-PAGE)
别名:
F-SRC-1, KAT13A, MGC129719, MGC129720, RIP160, SRC1, bHLHe42, bHLHe74
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关于此项目
NACRES:
NA.26
UNSPSC Code:
12352200
Assay:
≥80% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in E. coli
Concentration:
1000 μg/mL
biological source
human
recombinant
expressed in E. coli
assay
≥80% (SDS-PAGE)
form
frozen liquid
mol wt
~19.5 kDa
packaging
pkg of 10 μg
storage condition
avoid repeated freeze/thaw cycles
concentration
1000 μg/mL
color
clear colorless
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... NCOA1(8648)
Biochem/physiol Actions
Steroid receptor coactivator 1 (SRC1) is a transcriptional coactivator that mediates the activating functions of many of the nuclear hormone receptors. It is also known as NCoA1 and is a member of the SRC/p160 coactivator family. SRC1 has been shown to be over expressed in some cancers. SRC1 is a 160 kDa protein that contains several LXXLL motifs, which are involved in nuclear receptor interaction. The region 627-786 contains 3 LXXLL motifs that are involved in interaction with nuclear hormone receptorsand have been previously used in assays detecting ligand-dependent receptor-cofactor interactions. This protein contains the Tobacco Etch virus (TEV) protease site and can be cleaved using acTEV to yield untagged SRC1 RID. This protein will be useful for assays where a native untagged protein is desired.
Physical form
Clear and colorless frozen liquid solution
Preparation Note
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable