生物来源
human
重组
expressed in E. coli
方案
≥70% (SDS-PAGE)
表单
frozen liquid
分子量
~40 kDa
包装
pkg of 10 μg
储存条件
avoid repeated freeze/thaw cycles
颜色
clear colorless
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... GTF2A2(2958)
生化/生理作用
p12 is a small subunit γ of the transcription factor IIA and has been shown to be required for both basal and activated transcription. Recombinant p12, along with two other subunits (α and β) can potentiate transcriptional activation, whereas p12 along with a β subunit is able to function in an anti-repression.
外形
Clear and colorless frozen liquid solution
制备说明
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
J DeJong et al.
Proceedings of the National Academy of Sciences of the United States of America, 92(8), 3313-3317 (1995-04-11)
The human general transcription factor TFIIA is one of several factors involved in specific transcription by RNA polymerase II, possibly by regulating the activity of the TATA-binding subunit (TBP) of TFIID. TFIIA purified from HeLa extracts consists of 35-, 19-
J Ozer et al.
Genes & development, 8(19), 2324-2335 (1994-10-01)
TFIIA is thought to play an important role in transcriptional regulation in higher eukaryotes, but its precise function is unclear. A human cDNA encoding a protein with 45% identity to the small subunit of yeast TFIIA has been isolated. TFIIA
X Sun et al.
Genes & development, 8(19), 2336-2348 (1994-10-01)
Human TFIIA activity is composed of three subunits (alpha, beta, gamma). Here we report the isolation of a human cDNA clone encoding the gamma-subunit and the reconstitution of TFIIA activity from recombinant polypeptides (holo-TFIIA). Protein-protein interaction analysis established that the
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