biological source
rat
recombinant
expressed in E. coli
assay
≥97% (HPLC), ≥97% (SDS-PAGE)
form
lyophilized
potency
<0.2 ng/mL
mol wt
~16.3 kDa
packaging
pkg of 50 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
endotoxin, tested
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
rat ... Fgf2(54250)
General description
Fibroblast growth factor-2 (FGF-2) is a basic heparin binding growth factor and a profibrotic factor. The recombinant mouse FGF-2 is a single, non-glycosylated chain containing 145 amino acids and having a molecular weight of 16.3kDa.
Biochem/physiol Actions
Fibroblast growth factor-2 (FGF-2) stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells.
Physical form
Lyophilized from 1 mg/ml solution after extensive dialysis against 20 mM phosphate buffer, pH 7.4 and 130 mM NaCl.
Preparation Note
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in sterile water to 0.1–1 mg/mL.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Apocynin Attenuates Cardiac Injury in Type 4 Cardiorenal Syndrome via Suppressing Cardiac Fibroblast Growth Factor-2 With Oxidative Stress Inhibition.
Liu Y
Journal of the American Heart Association, 4(7), e001598-e001598 (2015)
FGF-18, a novel member of the fibroblast growth factor family, stimulates hepatic and intestinal proliferation.
Hu MC
Molecular and Cellular Biology, 18(10), 6063-6074 (1998)
Yayoi Yoshimura et al.
PloS one, 10(6), e0128288-e0128288 (2015-06-04)
Glioblastoma multiforme (GBM) is associated with high mortality due to infiltrative growth and recurrence. Median survival of the patients is less than 15 months, increasing requirements for new therapies. We found that both arsenic trioxide and 10058F4, an inhibitor of