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Merck
CN

SRP4145

IL-6 from rat

recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC)

别名:

MGI-2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, IFN-b2

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关于此项目

UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
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biological source

rat

recombinant

expressed in E. coli

assay

≥90% (HPLC), ≥90% (SDS-PAGE)

form

lyophilized

potency

<0.01 ng/mL ED50

mol wt

~21.7 kDa

packaging

pkg of 10 μg

impurities

endotoxin, tested

NCBI accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

rat ... Il6(24498)

General description

Interleukin- 6 (IL-6) is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. It is a pro-inflammatory cytokine. IL-6 originates from mononuclear phagocytes, T and B lymphocytes, vascular endothelial cells and fibroblasts. It has a role in various physiological and pathological processes. IL-6 plays an important role in intracellular signaling pathways. Recombinant rat IL-6 is a 21.7kDa protein containing 187 amino acid residues.

Physical form

Lyophilized without any additives.

Preparation Note

Reconstitute in 10 mM HCl to a concentration of 0.1-1.0 μg/μL. The solution can then be diluted into other aqueous buffers.
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

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Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine (2017)
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Preeclampsia is a multisystem disorder recognized as hypertension with proteinuria developing >20 weeks' gestation. Preeclampsia is associated with chronic immune activation characterized by increased T and B lymphocytes, cytokines, and antibodies activating the angiotensin II type I receptor (AT1-AA). Hypertension

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