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SRP4145

IL-6 from rat

Name: IL-6 from rat
Brand: SIGMA

recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC)

别名:

MGI-2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, IFN-b2

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关于此项目

UNSPSC Code:

12352202

NACRES:

NA.32

MDL number:

MFCD01323739

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属性

biological source

rat

recombinant

expressed in E. coli

assay

≥90% (HPLC), ≥90% (SDS-PAGE)

form

lyophilized

potency

<0.01 ng/mL ED₅₀

mol wt

~21.7 kDa

packaging

pkg of 10 μg

impurities

endotoxin, tested

NCBI accession no.

P20607

shipped in

wet ice

storage temp.

−20°C

Gene Information

rat ... Il6(24498)

说明

General description

Interleukin- 6 (IL-6) is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. It is a pro-inflammatory cytokine. IL-6 originates from mononuclear phagocytes, T and B lymphocytes, vascular endothelial cells and fibroblasts. It has a role in various physiological and pathological processes. IL-6 plays an important role in intracellular signaling pathways. Recombinant rat IL-6 is a 21.7kDa protein containing 187 amino acid residues.

Physical form

Lyophilized without any additives.

Preparation Note

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in 10 mM HCl to a concentration of 0.1-1.0 μg/μL. The solution can then be diluted into other aqueous buffers.

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

4G05L41450

70345

31045

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Meta-analysis of the role of IL-6 rs1800795 polymorphism in the susceptibility to prostate cancer: Evidence based on 17 studies.

Liu TZ

Medicine (2017)

Targeting interlukin-6 to relieve immunosuppression in tumor microenvironment.

Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine (2017)

Oxymatrine ameliorates myocardial injury by inhibiting oxidative stress and apoptosis via the Nrf2/HO-1 and JAK/STAT pathways in type 2 diabetic rats.

Yongpan Huang et al.

BMC complementary medicine and therapies, 23(1), 2-2 (2023-01-04)

The necessity of increasing the efficiency of organ preservation has encouraged researchers to explore the mechanisms underlying diabetes-related myocardial injuries. This study intended to evaluate the protective effects of oxymatrine (OMT) in myocardial injury caused by type 2 diabetes mellitus.

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全球贸易项目编号

货号	GTIN
SRP4145-10UG	04061837226212