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Merck
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About This Item

MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.32
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生物来源

human

重组

expressed in E. coli

方案

≥98% (HPLC)
≥98% (SDS-PAGE)

表单

lyophilized

效能

1.0-7.0 ng/mL

分子量

~38.2 kDa

包装

pkg of 10 μg

储存条件

avoid repeated freeze/thaw cycles

杂质

endotoxin, tested

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

基因信息

human ... VEGFA(7422)

一般描述

The gene VEGFA (vascular endothelial growth factor A) is a member of VEGF family of growth factors. The gene is localized to human chromosome 6p21.1. It contains eight exons interspaced by seven introns, spanning a length of 14 kb. The critical region of 2.36 kbp in human promoter lacks a consensus TATA box. However, it contains various consensus-binding sites for many transcriptional regulators.

生化/生理作用

The gene VEGFA (vascular endothelial growth factor A) encodes a secreted mitogen that is found to participate in physiological and pathological angiogenesis. It serves as a growth factor for endothelial cells and functions in the formation of new blood vessels during embryonic development and adulthood. It binds to two tyrosine kinase receptors VEGFR1 and VEGFR2 and functions in angiogenesis and maintenance of vasculature.

外形

Lyophilized with no additives.

重悬

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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