SRP5099
WNK1 (181-507), active, GST tagged human
PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
别名:
HSAN2, HSN2, KDP, KIAA0344, MGC163339, MGC163341, PRKWNK1, PSK, p65
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About This Item
UNSPSC代码:
12352202
NACRES:
NA.32
重组
expressed in baculovirus infected Sf9 cells
产品线
PRECISIO® Kinase
方案
≥70% (SDS-PAGE)
表单
buffered aqueous glycerol solution
比活
25-33 nmol/min·mg
分子量
~67 kDa
NCBI登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... WNK1(65125)
一般描述
WNK1 is a member of the WNK subfamily of serine/threonine protein kinases that is a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in WNK1 have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. WNK1 is a regulator of blood pressure and deficiency of this protein in mice lowers the blood pressure. WNK1 can regulate the Ca(2+) sensing and the subsequent Ca(2+)-dependent interactions mediated by synaptotagmin C2 domains and WNK1 exhibits additive CFTR inhibition.
外形
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
制备说明
after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles
法律信息
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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