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SRP5108

p21CIP1, GST tagged human

Name: p21CIP1, GST tagged human
Brand: SIGMA

recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

别名:

CAP20, CDKN1, CDKN1A, MDA-6, P21, SDI1, WAF1

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关于此项目

化学文摘社编号:

480063-57-8

NACRES:

NA.32

UNSPSC Code:

12352200

Form:

buffered aqueous glycerol solution

Assay:

≥70% (SDS-PAGE)

Biological source:

human

Recombinant:

expressed in E. coli

Mol wt:

~46 kDa

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属性

biological source

human

recombinant

expressed in E. coli

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

mol wt

~46 kDa

NCBI accession no.

NM_000389

application(s)

cell analysis

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... CDKN1A(1026)

说明

General description

CIP 1 (Cyclin-Dependent Kinase Inhibitor 1A) regulates cell cycle progression, terminal differentiation, and apoptosis. CIP1 was shown to be induced by p53 and to be a potent inhibitor of cyclin-dependent kinase (CDK) activity. DNA damage leads to increased expression of CIP1 in cyclin E-containing complexes and to an associated decrease in cyclin-dependent kinase activity. CIP1 is a critical downstream effector in the p53-specific pathway of growth control in mammalian cells.

Physical form

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

N281-6

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全球贸易项目编号

货号	GTIN
SRP5108-50UG	04061832942308