SRP5331
DYRK3, active, GST tagged human
PRECISIO®, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
别名:
DYRK5, RED, REDK
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
Form:
buffered aqueous glycerol solution
Assay:
≥70% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in E. coli
Mol wt:
~95 kDa
biological source
human
recombinant
expressed in E. coli
product line
PRECISIO®
assay
≥70% (SDS-PAGE)
form
buffered aqueous glycerol solution
specific activity
194-290 nmol/min·mg
mol wt
~95 kDa
technique(s)
cell culture | mammalian: suitable
NCBI accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... DYRK3(8444)
General description
DYRK3 or dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 is belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. DYRK3 expressed in E. coli undergoes tyrosine autophosphorylation and catalyzes phosphorylation of histones H3 and H2B in vitro. DYRK3 regulate different steps of the caveolar cycle. DYRK3 can promote cell survival through phosphorylation and activation of SIRT1. DYRK3 directly phosphorylate SIRT1 at Thr(522), promoting deacetylation of p53.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Preparation Note
After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable