产品名称
降钙素原 人, recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)
biological source
human
recombinant
expressed in E. coli
assay
≥97% (HPLC)
≥97% (SDS-PAGE)
form
lyophilized
potency
80 ng/mL
mol wt
12.796 kDa
packaging
pkg of 10 μg
technique(s)
cell culture | mammalian: suitable
impurities
Endotoxin, tested
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... N/A(796)
Application
人降钙素原已经用于 体外 血管渗透性试验。
Biochem/physiol Actions
降钙素原是降钙素的前激素。未加工的降钙素原水平在细菌感染、创伤或休克后显著升高。降钙素原也与急性胰腺炎患者的全身并发症相关。
General description
基因 CALC1（降钙素 1）定位于人类第 11 号染色体。CALC1 编码前降钙素。前降钙素在氨基端被内肽酶裂解产生降钙素原。降钙素原作为肽类激素发挥作用，主要由甲状腺的 C 细胞和肺的某些内分泌细胞产生。 在正常表达条件下，降钙素原立即裂解为 3 个特异性片段，N 端残基，降钙素和抗钙素。 大肠埃希菌中产生的重组人降钙素原 是一种单一的、非糖基化的多肽链，含有 116 个氨基酸，分子量为 12,796 道尔顿。
Physical form
从 10 mM 磷酸钠缓冲液 (pH 7.5) 冻干。
Preparation Note
打开前离心小瓶。在无菌 H？O 中复溶，浓度为 0.1 mg/mL。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
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