SRP6014
HGF human
recombinant, expressed in CHO cells, ≥97% (SDS-PAGE), ≥97% (HPLC)
别名:
F-TCF, HGF, HGFB, Hepatopoietin (HPTA), Scatter Factor (SF)
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关于此项目
Form:
lyophilized
Assay:
≥97% (HPLC), ≥97% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in CHO cells
Mol wt:
80.017 kDa
biological source
human
recombinant
expressed in CHO cells
assay
≥97% (HPLC), ≥97% (SDS-PAGE)
form
lyophilized
mol wt
80.017 kDa
packaging
pkg of 1 mg, pkg of 10 μg
technique(s)
cell culture | embryo: suitable
impurities
Endotoxin, tested
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... HGF(3082)
General description
Hepatocyte growth factor (HGF) is a multifunctional growth factor. HGF Human Recombinant produced in Chinese hamster ovary (CHO) is a heterodimer, non-glycosylated, polypeptide chain consisting of an α-chain of 463 amino acids and β-chain of 234 having a total molecular mass of 80.017kDa. The gene encoding this protein is localized on human chromosome 7q21.1. The HGF is purified by proprietary chromatographic techniques.
Biochem/physiol Actions
Hepatocyte growth factor (HGF) regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. HGF synergizes with interleukin-3 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to stimulate colony formation of hematopoietic progenitor cells in vitro and may, therefore, also modulate hematopoiesis. It is expressed in brain tumors.
Physical form
The protein was lyophilized from a concentrated (1 mg/ml) solution containing PBS pH 7.4 containing 0.05% Tween 20 and 100 mM L-arginine.
Preparation Note
Centrifuge the vial prior to opening. It is recommended to reconstitute the lyophilized Hepatocyte Growth Factor (HGF) in sterile 18 MΩcm-1 H2O not less than 100 μg/mL, which can then be further diluted to other aqueous solutions.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable