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Merck
CN

SRP6309

Proteinase 3 from human neutrophils

≥95% (SDS-PAGE)

别名:

AGP7, C-ANCA antigen, Leukocyte proteinase 3, Neutrophil proteinase 4, P29, Wegener autoantigen

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关于此项目

UNSPSC Code:
12352200
Form:
frozen liquid
Assay:
≥95% (SDS-PAGE)
Biological source:
human
Mol wt:
29 kDa
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biological source

human

assay

≥95% (SDS-PAGE)

form

frozen liquid

mol wt

29 kDa

packaging

pkg of 25 μg

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... AGP7(5657)

General description

Proteinase 3 is one of the serine proteinases localized in azurophil granules of polymorphonuclear leukocytes. It has been identified as the autoantigen of Wegener granulomatosis, a systemic vasculitis complicated by melomonocyte proliferation. It exhibits proteolytic activity towards a range of substrates. It is physiologically inhibited by α1-antitrypsin. The protein has been described as having antibiotic and growth-promoting properties and causing emphysema when administered by tracheal insufflation. Proteinase 3 (PR-3) is also known as myeloblastin and p29b.

Physical form

Frozen in 50 mM MES, pH 4.5 with 700 mM NaCl.


存储类别

11 - Combustible Solids

怎么回事?

nwg

闪点 (F)

Not applicable

闪点 (°C)

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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