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SRP6370

Aldolase A human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

别名:

ALDA, ALDOA, Fructose bisphosphate Aldolase A, GSD12

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关于此项目

NACRES:
NA.32
UNSPSC Code:
12352204
Biological source:
human
Recombinant:
expressed in E. coli
Assay:
≥95% (SDS-PAGE)
Form:
liquid
Mol wt:
41.5 kDa (384 aa, 1-364 aa + His Tag)
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biological source

human

recombinant

expressed in E. coli

assay

≥95% (SDS-PAGE)

form

liquid

mol wt

41.5 kDa (384 aa, 1-364 aa + His Tag)

packaging

pkg of 100 μg

concentration

1 mg/mL

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... ALDOA(226)

General description

Aldolase A (ALDOA) is a ubiquitous glycolytic enzyme expressed in developing embryos and in adult muscles. The gene encoding it is localized on human chromosome 16p11.2. Recombinant human Aldolase A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Biochem/physiol Actions

In glycolysis, aldolase A (ALDOA) catalyzes the reversible reaction of fructose-1,6-bisphosphate to glyceraldehydes-3-phosphate and dihydroxyacetone phosphate. It is involved in a wide range of cellular functions such as maintenance of striated muscle contraction, cell shape and mobility, actin filament organization and ATP biosynthetic process. High expression level of ALDOA is reported in various forms of malignant cancers, including human lung squamous, renal cell and hepatocellular carcinomas. ALDOA deficiency causes myopathy and hemolytic anemia.

Physical form

1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 100 mM NaCl and 10% glycerol.


存储类别

11 - Combustible Solids

怎么回事?

WGK 3

闪点 (F)

Not applicable

闪点 (°C)

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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