SRP6561
组织蛋白酶 K 活性 人
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
别名:
CTSK, CTSO, CTSO3
登录 查看组织和合同定价。
选择尺寸
关于此项目
NACRES:
NA.32
UNSPSC Code:
12352200
Assay:
≥90% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in E. coli
Concentration:
0.5 mg/mL
biological source
human
recombinant
expressed in E. coli
assay
≥90% (SDS-PAGE)
form
liquid
mol wt
23.5 kDa (115-329 aa)
packaging
pkg of 5 μg, pkg of 50 μg
concentration
0.5 mg/mL
technique(s)
activity assay: suitable
suitability
suitable for molecular biology
UniProt accession no.
application(s)
life science and biopharma
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... CTSK(1513)
General description
组织蛋白酶K是以组织蛋白酶原K表达的，而它是组织蛋白酶K的失活酶原。组织蛋白酶K是一种溶酶体半胱氨酸蛋白酶，是木瓜蛋白酶半胱氨酸蛋白酶家族的一部分。它在破骨细胞中表达。编码该蛋白的基因定位于人染色体1q21。
Biochem/physiol Actions
组织蛋白酶K在骨吸收和重塑中可发挥作用。它具有三重螺旋胶原水解酶活性。编码该蛋白质的基因中的突变已与脓毒症相连。
Physical form
溶于含50%甘油的25 mM Na2HPO4和500 mM NaCl (pH 7.0)的0.5 mg/mL溶液中。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Increased Circulating Cathepsin K in Patients with Chronic Heart Failure.
Zhao G, et al.
PLoS ONE, 10(8), e0136093-e0136093 (2015)
A Mutation in CTSK Gene in an Autosomal Recessive Pycnodysostosis Family of Chinese Origin.
Huang X, et al.
Calcified Tissue International, 96(5), 373-378 (2015)
Autocatalytic activation of human cathepsin K.
McQueney M S, et al.
The Journal of Biological Chemistry, 272(21), 13955-13960 (1997)
Cathepsin K as a biomarker of bone involvement in type 1 Gaucher disease.
Bobillo L J, et al.
Medicina clinica, 145(7), 281-287 (2015)
Andrew Wieczorek et al.
BMC biotechnology, 15, 112-112 (2015-12-17)
Triple helical collagens are the most abundant structural protein in vertebrates and are widely used as biomaterials for a variety of applications including drug delivery and cellular and tissue engineering. In these applications, the mechanics of this hierarchically structured protein
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持