SRP8026
Annexin V human
recombinant, expressed in E. coli, GST tagged, ≥95% (SDS-PAGE)
别名:
Annexin A5, Calphobindin I, EC 2.7.1.23, Endonexin II, Placental anticoagulantprotein I
产品名称
Annexin V human, recombinant, expressed in E. coli, GST tagged, ≥95% (SDS-PAGE)
biological source
human
recombinant
expressed in E. coli
tag
GST tagged
assay
≥95% (SDS-PAGE)
form
lyophilized
mol wt
~52 kDa
packaging
pkg of 100 μg
storage condition
avoid repeated freeze/thaw cycles
technique(s)
activity assay: suitable
color
white
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... ANXA5(308)
Application
Annexin V has been used to examine phosphorylation activity of ChaK1 (channel-kinase 1).
Biochem/physiol Actions
Annexins are a family of water-soluble proteins that bind to membranes and phospholipids in a calcium-dependent manner. They participate in several cellular functions, such as membrane fusion and cytoskeletal interaction. Annexin V is a potent anticoagulant and serves as a voltage-gated calcium channel when bound to membrane in vitro. It is found to inhibit phospholipase A2 and protein kinase C.
General description
Annexin V is a member of the annexin family of calcium and membrane-binding proteins that have anticoagulatory and anti-inflammatory properties. The encoded protein is 320 amino acid long and is folded into four domains, each having five α-helices, forming a superhelical globular structure. The ANX5 gene is mapped to human chromosome 4q26-q28 and spans a length of 28kb containing 13 exons and 12 introns.
Other Notes
Recombinant human annexin V fused to a GST-tag.
Physical form
Lyophilized from PBS, pH 7.4.
Preparation Note
Reconstitute with 100 μL deionized water.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
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