SRP8030
Fn14 (human): FC (human)
recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)
别名:
CD266, E1A-associated protein p300, FGF-inducible 14, Tumor necrosis factor receptor superfamily member 12A
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NACRES:
NA.32
UNSPSC Code:
51111800
Form:
lyophilized
Assay:
>95% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in HEK 293 cells
Mol wt:
~35 kDa by SDS-PAGE
产品名称
Fn14 (human): FC (human), recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)
biological source
human
recombinant
expressed in HEK 293 cells
assay
>95% (SDS-PAGE)
form
lyophilized
mol wt
~35 kDa by SDS-PAGE
packaging
pkg of 50 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
<0.1 EU/μg endotoxin, tested
color
white
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... TNFRSF12A(51330)
General description
TWEAK is a cytokine that controls proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK binds to Fn14, a highly inducible cell-surface receptor that is linked to several intracellular signalling pathways, including the nuclear factor-B (NF-kappaB) pathway. The TWEAK-Fn14 axis plays a beneficial role in tissue repair following acute injury and may contribute to cancer, chronic autoimmune diseases and acute ischaemic stroke.
Other Notes
The extracellular region of human FN14 (aa 28-75) is fused at the C-terminus to the Fc portion of human IgG1.
Physical form
Lyophilized from PBS.
Preparation Note
Reconstitute with 50 μL deionized water.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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