SRP8030
Fn14 (human): FC (human)
recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)
别名:
CD266, E1A-associated protein p300, FGF-inducible 14, Tumor necrosis factor receptor superfamily member 12A
生物来源
human
重组
expressed in HEK 293 cells
方案
>95% (SDS-PAGE)
表单
lyophilized
分子量
~35 kDa by SDS-PAGE
包装
pkg of 50 μg
储存条件
avoid repeated freeze/thaw cycles
杂质
<0.1 EU/μg endotoxin, tested
颜色
white
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... TNFRSF12A(51330)
一般描述
TWEAK is a cytokine that controls proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK binds to Fn14, a highly inducible cell-surface receptor that is linked to several intracellular signalling pathways, including the nuclear factor-B (NF-kappaB) pathway. The TWEAK-Fn14 axis plays a beneficial role in tissue repair following acute injury and may contribute to cancer, chronic autoimmune diseases and acute ischaemic stroke.
外形
Lyophilized from PBS.
制备说明
Reconstitute with 50 μL deionized water.
其他说明
The extracellular region of human FN14 (aa 28-75) is fused at the C-terminus to the Fc portion of human IgG1.
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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