产品名称
IL-1β 小鼠, recombinant, expressed in E. coli, untagged, >95% (SDS-PAGE)
biological source
mouse
recombinant
expressed in E. coli
conjugate
untagged
assay
>95% (SDS-PAGE)
form
lyophilized
mol wt
~17 kDa by SDS-PAGE
packaging
pkg of 10 μg
storage condition
avoid repeated freeze/thaw cycles
technique(s)
immunohistochemistry: suitable
impurities
<0.1 EU/μg endotoxin, tested
color
white
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Il1b(16176)
Biochem/physiol Actions
白介素-1β (IL-1β)可通过诱导IL-2释放、B细胞成熟和增殖以及成纤维细胞生长因子活性来刺激胸腺细胞增殖。在大多数情况下，IL-1β,需要炎症小体复合物被裂解和分泌。 该蛋白可调节肠中嗜酸性粒细胞的作用。
General description
白细胞介素-1β (IL-1β)由活化的巨噬细胞产生。它属于与炎症反应有关的IL-1蛋白家族。
Other Notes
小鼠IL-1beta（aa 118-269）未加标签。
Physical form
从PBS中冻干。
Preparation Note
用100 μL去离子水重组。
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
IL-1? in eosinophil-mediated small intestinal homeostasis and IgA production.
Jung Y
Mucosal Immunology, 8(4), 930-942 (2015)
Dongmin Xu et al.
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Perfluorooctane sulfonate (PFOS) is a persistent pollutant that exerts toxicity and induces cardiogenesis in humans and animals. Yet, the effect of PFOS exposure on cardiac toxicity in adult rats has, to our knowledge, not been reported and the mechanism still
Understanding the mechanism of IL-1? secretion.
Lopez-Castejon G and Brough D
Cytokine & Growth Factor Reviews, 22(4), 189-195 (2011)
Ruojia Ma et al.
Drug development research, 83(3), 735-744 (2021-12-21)
Type 2 diabetes mellitus (T2DM) is a metabolic risk factor associated with non-alcoholic liver disease (NAFLD). Schisandrin B (Sch B) is a promising agent for NAFLD. However, the actions of Sch B on diabetes-associated NAFLD and the underlying mechanisms are
Hai-Lei Guo et al.
Inflammation, 44(1), 358-370 (2020-10-13)
The inflammatory response involving interleukin-1β (IL-1β) has been thought to play an important role in the development of late-phase sepsis. However, in this study, we wanted to explore the possibility of using IL-1β to improve the prognosis of sepsis by
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