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Merck
CN

SRP8048

PEDF mouse

recombinant, expressed in CHO cells, FLAG® tagged, >95% (SDS-PAGE)

别名:

Caspin, PC cell-derived growth factor, Pigment epithelium-derived factor, Stromal cell-derived factor 3

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关于此项目

化学文摘社编号:
NACRES:
NA.32
UNSPSC Code:
12352202
Form:
lyophilized
Assay:
>95% (SDS-PAGE)
Biological source:
mouse
Recombinant:
expressed in CHO cells
Mol wt:
~47 kDa by SDS-PAGE
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biological source

mouse

recombinant

expressed in CHO cells

tag

FLAG® tagged

assay

>95% (SDS-PAGE)

form

lyophilized

mol wt

~47 kDa by SDS-PAGE

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

<0.01 EU/μg endotoxin, tested

color

white

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Serpinf1(20317)

General description

Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.

Physical form

Lyophilized from PBS.

Preparation Note

Reconstitute with 100 μL deionized water.

Other Notes

Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG®-tag.

Legal Information

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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