SRP8059
Jagged-2 (human): FC (human)
recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE)
别名:
Alpha-ketoglutarate-dependent dioxygenase FTO, Protein jagged-2, hJ2
产品名称
Jagged-2 (human): FC (human), recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE)
recombinant
expressed in HEK 293 cells
assay
≥90% (SDS-PAGE)
form
lyophilized
mol wt
~150 kDa by SDS-PAGE
impurities
<0.1 EU/μgtested
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... JAG2(3714)
General description
Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.
Other Notes
Human Jagged-2 (aa 1-1054) is fused at the C-terminus to the Fc portion of human IgG.
Physical form
Lyophilized. Contains PBS + 0.02 % CHAPS.
Preparation Note
Reconstitute with 100μl sterile water.
存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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