T0175
Troponin T from human heart
≥60% (SDS-PAGE), lyophilized powder
别名:
Tn-T
产品名称
Troponin T from human heart, ≥60% (SDS-PAGE), lyophilized powder
biological source
human heart
form
lyophilized powder
purified by
affinity chromatography
concentration
≥60% (SDS-PAGE)
technique(s)
ELISA: suitable
solubility
10 mM HCl: 500 μg/mL, clear, colorless
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Quality Level
Gene Information
human ... TNNT2(7139)
Application
Troponin T from human heart has been used in competitive enzyme-linked immunosorbent assay (ELISA) for the quantification of troponin T (TnT).
Biochem/physiol Actions
The tropomyosin-binding subunit of troponin. The cardiac troponin T gene (TNNT2) helps to connect the troponin complex to α-tropomyosin, thereby participates in the modulation of contractile function.
General description
The cardiac troponin T gene (TNNT2) is located on human chromosome 1 and spans around 17kb. It codes for a 288-amino-acid peptide of 36−39kDa.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Inherited cardiomyopathies
Emery and Rimoin's Principles and Practice of Medical Genetics, 1-38 (2013)
A skeletal muscle troponin T specific ELISA based on the use of an antibody against the soluble troponin T (16-31) fragment
Tsitsilonis O E, et al.
Journal of Immunological Methods, 268(2), 141-148 (2002)
Nikita Sitkov et al.
Micromachines, 12(6) (2021-07-03)
The problems of chronic or noncommunicable diseases (NCD) that now kill around 40 million people each year require multiparametric combinatorial diagnostics for the selection of effective treatment tactics. This could be implemented using the biosensor principle based on peptide aptamers
商品
Troponin together with tropomyosin, regulate the binding of myosin to actin. Troponin is a trimeric protein composed of Troponin subunits I, C and T. Troponin C binds calcium ions, Troponin T binds to tropomyosin and troponin I binds to actin
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