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T0203

TGFβR2 (190-端)，活性，GST 标记人

Name: TGFβR2 (190-端)，活性，GST 标记 人
Brand: SIGMA

PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

别名:

AAT3, FAA3, HPNCC6, MFS2, RIIC, TAAD2, TGFR-2

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关于此项目

NACRES:

NA.32

UNSPSC Code:

12352200

Form:

buffered aqueous glycerol solution

Assay:

≥70% (SDS-PAGE)

Biological source:

human

Recombinant:

expressed in baculovirus infected Sf9 cells

Mol wt:

~68 kDa

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属性

biological source

human

Quality Segment

100

recombinant

expressed in baculovirus infected Sf9 cells

product line

PRECISIO^® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

6-8 nmol/min·mg

mol wt

~68 kDa

UniProt accession no.

P37173

application(s)

cell analysis

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... TGFBR2(7048)

说明

General description

Transforming growth factor β receptor 2 (TGFBR2) is a member of the TGFβ receptor subfamily and is a serine/threonine protein kinase. The gene encoding this protein is localized on human chromosome 3p24.1.

Biochem/physiol Actions

Transforming growth factor β receptor 2 (TGFBR2)-induced protein phosphorylation plays a key role in signal transduction that leads to mitogenic responses. The TGFBR2 receptor transmits signals from the cell surface to the nucleus and provides instructions for making transforming growth factor (TGF)-β type II receptor. Mutations in TGFBR2 gene have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome and the development of various types of tumors.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c