T0203
TGFβR2 (190-端)，活性，GST 标记 人
PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
别名:
AAT3, FAA3, HPNCC6, MFS2, RIIC, TAAD2, TGFR-2
生物来源
human
质量水平
重组
expressed in baculovirus infected Sf9 cells
产品线
PRECISIO® Kinase
方案
≥70% (SDS-PAGE)
表单
buffered aqueous glycerol solution
比活
6-8 nmol/min·mg
分子量
~68 kDa
UniProt登记号
应用
cell analysis
运输
dry ice
储存温度
−70°C
基因信息
human ... TGFBR2(7048)
一般描述
Transforming growth factor β receptor 2 (TGFBR2) is a member of the TGFß receptor subfamily and is a serine/threonine protein kinase. The gene encoding this protein is localized on human chromosome 3p24.1.
生化/生理作用
Transforming growth factor β receptor 2 (TGFBR2)-induced protein phosphorylation plays a key role in signal transduction that leads to mitogenic responses. The TGFBR2 receptor transmits signals from the cell surface to the nucleus and provides instructions for making transforming growth factor (TGF)-β type II receptor. Mutations in TGFBR2 gene have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome and the development of various types of tumors.
外形
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
法律信息
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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