T0307
四丁酚醛
BioXtra
别名:
含有甲醛和环氧乙烷的4-（1,1,3,3-四甲基丁基）苯酚聚合物
产品名称
四丁酚醛, BioXtra
InChI
1S/C14H22O.C2H6O2.CH2O/c1-13(2,3)10-14(4,5)11-6-8-12(15)9-7-11;3-1-2-4;1-2/h6-9,15H,10H2,1-5H3;3-4H,1-2H2;1H2
SMILES string
[H]C([H])=O.OCCO.CC(C)(C)CC(C)(C)c1ccc(O)cc1
InChI key
GWJOFBXSBDVUMH-UHFFFAOYSA-N
description
non-ionic
product line
BioXtra
impurities
<0.0005% Phosphorus (P)
ign. residue
<1.0%
CMC
0.018 mM
transition temp
cloud point 94.3 °C
anion traces
chloride (Cl-): <0.05%
sulfate (SO42-): <0.6%
cation traces
Al: <0.0005%
Ca: <0.0005%
Cu: <0.0005%
Fe: <0.001%
K: <0.005%
Mg: <0.0005%
NH4+: <0.05%
Na: <0.5%
Pb: <0.001%
Zn: <0.0005%
Quality Level
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Application
在一项研究中使用泰洛沙泊评估重组人胰岛素的肺部吸收增强。 也用于研究蛋氨酸和胆碱缺乏时促进肝内脂肪酸蓄积的代谢途径。
General description
它是烷基芳基聚醚醇类的非离子液体聚合物。 可用作表面活性剂。
泰洛沙泊是一种生物相容性表面活性剂
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Aki Uchida et al.
Frontiers in physiology, 3, 26-26 (2012-03-01)
Obesity results in abnormally high levels of triglyceride (TG) storage in tissues such as liver, heart, and muscle, which disrupts their normal functions. Recently, we found that lean mice challenged with high levels of dietary fat store TGs in cytoplasmic
David P Macfarlane et al.
American journal of physiology. Endocrinology and metabolism, 300(2), E402-E409 (2010-12-02)
The pathological mechanisms that distinguish simple steatosis from steatohepatitis (or NASH, with consequent risk of cirrhosis and hepatocellular cancer) remain incompletely defined. Whereas both a methionine- and choline-deficient diet (MCDD) and a choline-deficient diet (CDD) lead to hepatic triglyceride accumulation
Jianheng Zheng et al.
Die Pharmazie, 67(5), 448-451 (2012-07-07)
Natural pulmonary surfactant (PS) and its artificial substitute phospholipid hexadecanol tyloxapol (PHT) are effective absorption enhancers on promoting recombinant human insulin (Rh-ins) absorption in vivo, but the in vitro efficacy and underlying mechanism remains unclear. In the current study, the
Formulation of Tyloxapol niosomes for encapsulation, stabilization and dissolution of anti-tubercular drugs
Mehta, S. and N. Jindal
Colloids and Surfaces. B, Biointerfaces, 434?441-434?441 (2013)
Martina Theresa Hackl et al.
Nature communications, 10(1), 2717-2717 (2019-06-22)
Hepatic steatosis develops when lipid influx and production exceed the liver's ability to utilize/export triglycerides. Obesity promotes steatosis and is characterized by leptin resistance. A role of leptin in hepatic lipid handling is highlighted by the observation that recombinant leptin
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