T0632
硫代乙醇酸钠
≥96.5% (iodometric)
别名:
巯乙酸 钠盐, 巯基乙酸 钠盐
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线性分子式:
HSCH2COONa
化学文摘社编号:
分子量:
114.10
Beilstein:
4569109
EC 号:
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.25
质量水平
方案
≥96.5% (iodometric)
表单
powder
颜色
white to off-white
有效pH范围
6.7 (20 °C, 100 g/L)
mp
>300 °C (lit.)
溶解性
water: ~609.1 g/L at 20 °C (OECD Test Guideline 105)
储存温度
−20°C
SMILES字符串
[Na+].[O-]C(=O)CS
InChI
1S/C2H4O2S.Na/c3-2(4)1-5;/h5H,1H2,(H,3,4);/q;+1/p-1
InChI key
GNBVPFITFYNRCN-UHFFFAOYSA-M
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应用
巯基乙酸钠用作：
- 用作富集培养基中的生长补充剂，研究其对弓形菌属的影响
- 在流感血凝素制剂中，减少二硫化物介导的交联反应和早期效力损失
- 电子显微镜下
生化/生理作用
巯基乙酸钠是细菌学研究中用来保持培养基还原条件的常用试剂。巯基乙酸还能够通过将蛋白质硫醇基维持在还原状态，保护酶，防止酶失活。巯基乙酸培养基经常用于炎症研究，在体内诱导中性粒细胞和巨噬细胞响应。
巯基乙酸钠用作还原剂，适用厌氧菌和微需氧菌生长。
免责声明
在室温下，在水中浓度超过70%情况下，每月会形成1-2%的硫代乙丙交酯，在酸性或碱性条件下，会水解成原来的自由化合物。70%溶液在空气中氧化，但当密封后在室温下稳定。巯基乙酸盐在储存过程中可能会丧失纯度。去除空气并不会改善稳定度。
警示用语：
Danger
危险分类
Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Chronic 3 - Met. Corr. 1 - Skin Sens. 1B
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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