T0656
1,3,4,6-四氯-3α,6α-二苯基甘脲
别名:
Iodo-Gen®, NSC 4462
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关于此项目
经验公式（希尔记法）:
C16H10Cl4N4O2
化学文摘社编号:
分子量:
432.09
MDL编号:
UNSPSC代码:
12352101
PubChem化学物质编号:
NACRES:
NA.22
储存温度
2-8°C
质量水平
SMILES字符串
ClN1C(=O)N(Cl)C2(N(Cl)C(=O)N(Cl)C12c3ccccc3)c4ccccc4
InChI
1S/C16H10Cl4N4O2/c17-21-13(25)23(19)16(12-9-5-2-6-10-12)15(21,11-7-3-1-4-8-11)22(18)14(26)24(16)20/h1-10H
InChI key
FJQZXCPWAGYPSD-UHFFFAOYSA-N
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应用
用作氧化剂的放射性碘化用碘化试剂
用于氯胺-T 比较研究的试剂
用于氧化咪唑的试剂
用于氯胺-T 比较研究的试剂
用于氧化咪唑的试剂
法律信息
Iodo-Gen is a registered trademark of Pierce Biotechnology, Inc.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Bernard M Tijink et al.
European journal of nuclear medicine and molecular imaging, 36(8), 1235-1244 (2009-03-05)
The human monoclonal antibody (MAb) fragment L19-SIP is directed against extra domain B (ED-B) of fibronectin, a marker of tumour angiogenesis. A clinical radioimmunotherapy (RIT) trial with (131)I-L19-SIP was recently started. In the present study, after GMP production of (124)I
Th M Behr et al.
Nuklearmedizin. Nuclear medicine, 41(2), 71-79 (2002-05-07)
Simple and reliable methodologies for radioiodination of proteins and peptides are described. The labeling systems are easy to assemble, capable of radioiodinating any protein or, with slight modifications, also peptide (molecular mass 1000-300,000) from kBq to GBq levels of activity
Miro J Eigenmann et al.
The Journal of physiology, 595(24), 7311-7330 (2017-09-30)
For therapeutic antibodies, total tissue concentrations are frequently reported as a lump sum measure of the antibody in residual plasma, interstitial fluid and cells. In terms of correlating antibody exposure to a therapeutic effect, however, interstitial pharmacokinetics might be more
Ulla Lund et al.
American journal of physiology. Renal physiology, 284(6), F1226-F1234 (2003-03-07)
The size and charge-selective properties of the glomerular barrier are partly controversial. Glomerular sieving coefficients (theta) for proteins have rarely been determined noninvasively before in vivo. Therefore, theta was assessed vs. glomerular filtration rate (GFR; (51)Cr-EDTA clearance) in intact rats
Helge Wiig et al.
The Journal of physiology, 567(Pt 2), 557-567 (2005-07-05)
Knowledge of macromolecular distribution volumes is essential in understanding fluid transport within normal and pathological tissues. In this study in vivo we determined the distribution volumes of several macromolecules, including one monoclonal antibody, in tumours and tested whether charges associated
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