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Merck
CN

T0675

[D-Ala2]-Deltorphin II

≥97% (HPLC)

别名:

Tyr-D-Ala-Phe-Glu-Val-Val-Gly amide

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关于此项目

经验公式（希尔记法）:
C38H54N8O10
化学文摘社编号:
122752-16-3
分子量:
782.88
NACRES:
NA.32
PubChem Substance ID:
24899907
UNSPSC Code:
12352209
MDL number:
MFCD00080072
Form:
powder
Assay:
≥97% (HPLC)
Biological source:
synthetic (organic)

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产品名称

[D-Ala2]-Deltorphin II, ≥97% (HPLC)

InChI

1S/C38H54N8O10/c1-20(2)31(37(55)41-19-29(40)48)46-38(56)32(21(3)4)45-35(53)27(15-16-30(49)50)43-36(54)28(18-23-9-7-6-8-10-23)44-33(51)22(5)42-34(52)26(39)17-24-11-13-25(47)14-12-24/h6-14,20-22,26-28,31-32,47H,15-19,39H2,1-5H3,(H2,40,48)(H,41,55)(H,42,52)(H,43,54)(H,44,51)(H,45,53)(H,46,56)(H,49,50)/t22-,26+,27+,28+,31+,32+/m1/s1

SMILES string

CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)C)C(=O)NCC(N)=O

InChI key

NUNBRHVOPFWRRG-RCEFDBTISA-N

biological source

synthetic (organic)

assay

≥97% (HPLC)

form

powder

storage temp.

−20°C

Quality Level

200

Gene Information

human ... OPRD1(4985), OPRK1(4986), OPRM1(4988)
mouse ... Oprd1(18386), Oprm1(18390)
rat ... Oprd1(24613), Oprm1(25601)

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Biochem/physiol Actions

Selective δ2 opioid receptor agonist

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCC1825
SLBZ8418
SLBS8359
SLBR8129V
SLBP5876V

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H Beaudry et al.
Neuroscience, 161(2), 381-391 (2009-03-31)
In the present study, we asked whether multiple intrathecal injections of deltorphin II, a selective delta opioid receptor (DOPR) agonist, induced DOPR tolerance in three behavioral assays. Unilateral inflammation caused by complete Freund's adjuvant (CFA) injection into the rat or
Agnès Poirier et al.
Drug metabolism and disposition: the biological fate of chemicals, 36(12), 2434-2444 (2008-09-24)
The use of in vitro data for quantitative predictions of transporter-mediated elimination in vivo requires an accurate estimation of the transporter Michaelis-Menten parameters, V(max) and K(m), as a first step. Therefore, the experimental conditions of in vitro studies used to
Xiaoli Zeng et al.
The Journal of surgical research, 169(2), 267-276 (2010-05-07)
Studies have documented the beneficial roles of δ opioid receptor (OR) agonist for hemorrhagic shock. However, the myocardial protection roles and the mechanisms of hemodynamic stability during resuscitation of δ-OR agonist have not been explored. This study was designed to
V Otis et al.
Neuroscience, 183, 221-229 (2011-04-05)
Over the past few years, significant progress has been made in cancer therapy. Indeed, the lifespan of cancer patients has significantly increased. Although patients live longer, cancer-related pain remains a daily problem affecting their quality of life, especially when metastases
Sudha Ananth et al.
Journal of pharmaceutical sciences, 101(1), 154-163 (2011-09-10)
The sodium-coupled oligopeptide transporters 1 and 2 (SOPT1 and SOPT2) transport peptides consisting of at least five amino acids and show potential for the delivery of therapeutically relevant peptides/peptidomimetics. Here, we examined the expression of these two transporters in the
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