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Merck
CN

T0875

Sigma-Aldrich

牛磺脱氧胆酸钠 水合物

≥95% (HPLC)

别名:

2-([3α12α-二羟基-24-氧-5β-胆碱-24-酰基]氨基)乙醇磺酸, 牛磺脱氧胆酸 钠盐 水合物

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关于此项目

线性分子式:
C26H44NO6SNa · xH2O
CAS Number:
分子量:
521.69 (anhydrous basis)
Beilstein:
3901204
MDL编号:
UNSPSC代码:
12161900
PubChem化学物质编号:
NACRES:
NA.25
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描述

anionic

质量水平

方案

≥95% (HPLC)

分子量

micellar avg mol wt 3100

聚集数

6

CMC

1-4 mM (20-25°C)

应用

sample preservation

SMILES字符串

O.[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C26H45NO6S.Na.H2O/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3;;/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);;1H2/q;+1;/p-1/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-;;/m1../s1

InChI key

OLPIZAYYAVQETM-GGPRKOIFSA-M

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应用

已有一项研究采用水合牛去氧胆酸钠,研究了胆盐亚胶束浓度对脂质双层膜的影响。 它也在一项研究中被用于研究蛋白质-表面活性剂混合物的多态行为。
胆盐相关的阴离子清洗剂,用于分离膜蛋白,包括线粒体内膜蛋白。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Barbara Orioni et al.
The journal of physical chemistry. B, 110(24), 12129-12140 (2006-06-28)
Mixtures containing water, bovine serum albumin (BSA), and sodium taurodeoxycholate (NaTDC), a component of the bile in mammals, have been investigated in a wide range of composition and pH. Depending on the concentration of both solutes and the pH, solutions
Jing-Yi Ye et al.
International journal of nanomedicine, 15, 6503-6518 (2020-09-15)
A non-lipolysis nanoemulsion (NNE) was designed to reduce the first-pass metabolism of raloxifene (RAL) by intestinal UDP-glucuronosyltransferases (UGTs) for increasing the oral absorption of RAL, coupled with in vitro and in vivo studies. In vitro stability of NNE was evaluated
Monalisa Mohapatra et al.
Langmuir : the ACS journal of surfaces and colloids, 27(22), 13461-13467 (2011-10-07)
The interaction of submicellar concentrations of various physiologically important unconjugated [sodium deoxycholate (NaDC), sodium cholate (NaC)] and conjugated [sodium glycodeoxycholate (NaGDC), sodium glycocholate (NaGC), sodium taurodeoxycholate (NaTDC), sodium taurocholate (NaTC)] bile salts with dipalmitoylphosphatidylcholine (DPPC) and dimyristoylphosphatidylcholine (DMPC) small unilamellar
Nitya Subrahmanian et al.
Genetics, 214(4), 895-911 (2020-02-23)
Complex I is the first enzyme involved in the mitochondrial electron transport chain. With >40 subunits of dual genetic origin, the biogenesis of complex I is highly intricate and poorly understood. We used Chlamydomonas reinhardtii as a model system to
Malinda Salim et al.
Molecular pharmaceutics, 17(3), 885-899 (2020-02-06)
Techniques enabling in situ monitoring of drug solubilization and changes in the solid-state of the drug during the digestion of milk and milk-based formulations are valuable for predicting the effectiveness of such formulations in improving the oral bioavailability of poorly

实验方案

Investigate bile acid roles in gut hormone profiles and glycemic control, vital for clinical labs exploring potential mechanisms.

相关内容

Bile Acids (BA) are synthesized in the liver and play important roles in cholesterol homeostasis, absorption of vitamins and lipids, and various key metabolic processes.

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