T103
三氟哌丁苯 盐酸盐
别名:
4′-Fluoro-4-[4-hydroxy-4-(α,α,α-trifluoro-m tolyl)piperidino]butyrophenone hydrochloride, R 2498, Triperidol
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关于此项目
经验公式（希尔记法）:
C22H23F4NO2 · HCl
化学文摘社编号:
分子量:
445.88
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
218-170-1
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated
assay
≥98% (HPLC)
Quality Segment
form
solid
storage condition
desiccated
color
white to off-white
solubility
DMSO: ≥20 mg/mL, H2O: soluble, ethanol: moderately soluble
SMILES string
Cl.OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c3cccc(c3)C(F)(F)F
InChI
1S/C22H23F4NO2.ClH/c23-19-8-6-16(7-9-19)20(28)5-2-12-27-13-10-21(29,11-14-27)17-3-1-4-18(15-17)22(24,25)26;/h1,3-4,6-9,15,29H,2,5,10-14H2;1H
InChI key
VYGQXRZAHIZHQV-UHFFFAOYSA-N
Gene Information
human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816)
Application
The interaction of Trifluperidol hydrochloride with NMDA receptors was studied in rat brain buffy coat membranes.
Biochem/physiol Actions
Trifluperidol is a dopamine receptor antagonist with antipsychotic effects used in the treatment of schizophrenia. This neuroleptic penetrates the brain and also affects the glial cells leading to increased release of proinflammatory cytokines. It also alters the metabolism of carbohydrates and amino acids in the brain cortex.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| T103-25MG | 04061832093789 |
| T103-100MG | 04061832086187 |