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Merck
CN

T1126

甲状腺球蛋白 来源于猪甲状腺腺体

powder

别名:

TG human

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关于此项目

化学文摘社编号:
UNSPSC Code:
12352202
EC Number:
232-721-3
NACRES:
NA.61
MDL number:
Form:
powder
Biological source:
Porcine thyroid
Mol wt:
~670 kDa
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biological source

Porcine thyroid

Quality Level

form

powder

mol wt

~670 kDa

composition

Iodine, ≥0.3%

nitrogen analysis

14.0-17.5% total

technique(s)

protein purification: suitable

ash

≤4%

pI 

4.58

UniProt accession no.

storage temp.

−20°C

Gene Information

pig ... TG(100156471)

Biochem/physiol Actions

甲状腺球蛋白已被证明可调节包括碘化钠同向转运蛋白和Pendrin在内的碘转运蛋白的转录。
甲状腺球蛋白是一种参与碘代谢的主要蛋白质。它由一种储存在甲状腺中的含碘蛋白质组成,当甲状腺受到垂体促甲状腺激素(TSH)的刺激时,就会转化为循环中的甲状腺素。甲状腺球蛋白常被用作产生抗体的载体蛋白。它作为载体蛋白的优势来自于其大量的酪氨酸残基,可以通过重氮反应进行偶联。

Preparation Note

用水 (20 mg/mL) 复溶时,观察到浑浊溶液和一些不溶物。

Other Notes

电泳异构。


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

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Kotaro Kelley et al.
Nature communications, 13(1), 1857-1857 (2022-04-08)
Cryo-FIB/SEM combined with cryo-ET has emerged from within the field of cryo-EM as the method for obtaining the highest resolution structural information of complex biological samples in-situ in native and non-native environments. However, challenges remain in conventional cryo-FIB/SEM workflows, including
Sanathana Konugolu Venkata Sekar et al.
Scientific reports, 8(1), 10015-10015 (2018-07-04)
Thyroid plays an important role in the endocrine system of the human body. Its characterization by diffuse optics can open new path ways in the non-invasive diagnosis of thyroid pathologies. Yet, the absorption spectra of tyrosine and thyroglobulin-key tissue constituents
Yang Li et al.
International journal of endocrinology, 2021, 9439344-9439344 (2021-08-24)
45 healthy and adult female SD rats were randomly divided into three groups: normal control group, EAT model group, and selenium yeast supplement EAT group. The EAT model rats were induced by subcutaneous injection of porcine thyroglobulin and fed with



全球贸易项目编号

货号GTIN
T1126-500MG04061833493496
T1126-100MG04061833435281
T1126-1G04061826658659