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T1270

Sigma-Aldrich

硫胺 盐酸盐

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

别名:

硫胺素 盐酸盐, 维生素 B 1 盐酸盐

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25 G
¥795.32
100 G
¥1,613.76

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25 G
¥795.32
100 G
¥1,613.76

About This Item

经验公式（希尔记法）:
C12H17ClN4OS · HCl
CAS Number:
67-03-8
分子量:
337.27
Beilstein:
3851771
EC 号:
200-641-8
MDL编号:
MFCD00012780
UNSPSC代码:
12352207
eCl@ss:
34058006
PubChem化学物质编号:
24899952
NACRES:
NA.75

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生物来源

synthetic (organic)

质量水平

200

产品线

BioReagent

方案

≥99.0% (HPLC)

表单

powder

分子量

Mw 337.27 g/mol

技术

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

颜色

white

mp

250 °C (dec.) (lit.)

溶解性

H2O: 50 mg/mL, clear, colorless

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相关类别

一般描述

硫胺素或维生素B1带正电荷，是所有组织的基本成分。它在骨骼肌、肝脏、肾脏、心脏和大脑中含量较高。[1]硫胺素由一个嘧啶环组成，通过亚甲基桥连接到一个噻唑环。 [2]

应用

盐酸硫胺素已被用作以下物质的组分：
  • 维生素浓缩原液，用于制备培养火山富盐菌的Hv-Ca培养基[3]
  • 三乙酸磷酸盐（TAP）培养基，用于培养雪衣藻[4]
  • 改良Bold 3N培养基，用于培养小球藻[5]

生化/生理作用

硫胺素通过硫胺素二磷酸激酶进入细胞膜后转化为二磷酸硫胺素。[1]二磷酸硫胺素是一种活性辅因子，对于许多酶的机制至关重要，这些酶参与柠檬酸循环、糖酵解途径、支链氨基酸降解和磷酸戊糖通路。[6]硫胺素参与将食物转化为能量的过程，供中枢和外周神经系统运作使用。该维生素的低水平与谵妄、Wernicke脑病和Wernicke-Korsakoff综合征有关。[7]盐酸硫胺素是培养细胞能量代谢和氨基酸合成所必需的。它存在于许多经典和无血清配方中。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H319

危险分类

Eye Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    BCCN2484
    BCCN0070
    BCCL5599
    BCCM3832
    BCCK4076

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