T1512
四咪唑 盐酸盐
powder, ≥99% (TLC)
别名:
(±)-2,3,5,6-四氢-6-苯基咪唑并[2,1-b]噻唑 盐酸盐
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关于此项目
经验公式（希尔记法）:
C11H12N2S · HCl
化学文摘社编号:
分子量:
240.75
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
225-799-5
MDL number:
Beilstein/REAXYS Number:
4358989
产品名称
四咪唑 盐酸盐, phosphatase inhibitor
biological source
synthetic (organic)
Quality Level
description
alkaline phosphatase inhibitor
assay
≥99% (TLC)
form
powder
mp
266-267 °C (lit.)
solubility
water: 50 mg/mL, clear, colorless
SMILES string
Cl[H].C1CN2CC(N=C2S1)c3ccccc3
InChI
1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H
InChI key
LAZPBGZRMVRFKY-UHFFFAOYSA-N
Application
四咪唑衍生物作为碱性磷酸酶抑制剂的结构-活性关系。
适于抑制各种哺乳动物碱性磷酸酶（例如，肝、肾、胎盘、骨和肿瘤）。肠道碱性磷酸酶仅受到轻微的抑制。
Other Notes
外消旋形式的左旋咪唑。
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Nicolas T Chartier et al.
Nature physics, 17(8), 920-925 (2021-11-16)
Oocytes are large cells that develop into an embryo upon fertilization1. As interconnected germ cells mature into oocytes, some of them grow-typically at the expense of others that undergo cell death2-4. We present evidence that in the nematode Caenorhabditis elegans
Kinetics and inhibition of alkaline phosphatases from canine tissues.
H Van Belle
Biochimica et biophysica acta, 289(1), 158-168 (1972-11-10)
Omer Yuval et al.
PLoS computational biology, 17(7), e1009185-e1009185 (2021-07-20)
Complex dendritic trees are a distinctive feature of neurons. Alterations to dendritic morphology are associated with developmental, behavioral and neurodegenerative changes. The highly-arborized PVD neuron of C. elegans serves as a model to study dendritic patterning; however, quantitative, objective and
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| T1512-5G | 04061837337697 |
| T1512-2G | 04061833632260 |
| T1512-10G | 04061833632253 |